(W.S.P)

For Veterinary Use Only

Composition :

Each 1 gm contains:
Doxycycline ( as Hyclate) 260 mg

Properties:

Doxycycline is a semisynthetic tetracycline derivative. It acts by inhibiting protein synthesis at the ribosomal level, predominantly by binding to the 30S ribosomal subunits of bacteria. Doxycycline is a broad-spectrum antibiotic. It exhibits a wide range of activity against Gram-positive and Gram-negative, aerobic and anaerobic pathogens, especially against Pasteurella multocida and Mycoplasma hyopneumoniae isolated from pig respiratory infections and Mycoplasma gallisepticum associated with clinical respiratory infections in chickens and turkeys

Indications:

-Pigs (post-weaning): treatment of Mycoplasmal pneumonia (enzootic pneumonia) caused by Mycoplasma hyopneumoniae.
– Broilers chickens and Broilers turkeys: treatment of chronic respiratory disease and infectious sinusitis caused by Mycoplasma gallisepticum.

Target Species:

-Pigs (post-weaning), Broilers chickens and Broilers turkeys.

Dosage & administration:

– Route of administration: Orally in the drinking water.
For whole product:
– Pigs (post-weaning): 1.5 gm. of product / 20 kg. b. wt. In drinking water, daily, for 5 consecutive days.
– Broilers chickens: 0. 8 g / Liter drinking water, daily, for 5 consecutive days.
– Broilers turkeys: 1 g / Liter drinking water, daily, for 5 consecutive days

Warnings and precautions:

• Do not administer concurrently with feed overloaded with polyvalent cations such as Ca2+, Mg2+, Zn2+ and Fe3+ because the formation of doxycycline complexes with these cations is possible. It is advised that
  In case of reaction after exposure to the product (rash for example), consult a doctor the interval between administration of other products containing polyvalent cations should be 1-2 hours because they limit the absorption of tetracycline.
  Do not administer together with antacids, kaolin or iron preparations.
  Do not administer in conjunction with bactericidal antibiotics such as beta-lactames as tetracyclines are bacteriostatic antimicrobials.

Contra-indications

– Do not use in case of known hypersensitivity to tetracyclines or to the excipient.
– Do not use when tetracycline resistance has been detected in the herd/flock due to the potential for cross-resistance.
-Do not use in animals with impaired liver or kidney function

Withdrawal periods:

– Pigs (post-weaning): Meat and offal: 10days.
– Broilers chickens: Meat and offal: 10 days.
– Broilers turkeys: Meat and offal: 10 days.
Not authorized for use in birds producing eggs for human consumption.

Side – Effects:

As for all tetracyclines, on rare occasions allergic reactions and photosensitivity may occur. If suspected adverse reactions occur, treatment should be discontinued.

Storage condition:

Store at a temperature not exceeding 30°C and used immediately after opening and after Reconstitution

Packaging:

Transparent Plastic (LDPE) bag containing 100,250,500 and 1000 gm. of the Product in
(HDPE) White plastic Jar with an outer label with (HDPE) White
plastic cap