Each 1000 gm contains:
Tylvalosin (Tylvalosin tartrate) 170 g
Tylvalosin is a macrolide antibiotic that has antibacterial activity against Gm +ve, some Gm –ve organisms & Mycoplasma. It acts by inhibiting protein synthesis in the bacterial cell. Macrolides interfere with protein synthesis by reversibly binding to the 50S ribosome subunit. It binds to the donor site & prevent the translocation necessary for keeping the peptide chain growing. Its effect is essentially confined to rapidly dividing organisms. Macrolides are generally considered bacteriostatic& Mycoplasmastatic. Resistance to tylvalosin by Mycoplasma hyopneumoniae Lawsonia intracellularis has not been reported or found in the field to date. No breakpoint for Brachyspira hyodysenteriae has been established. Generally strains of B. hyodysenteriae have higher MIC values in cases of resistance against other macrolides, such as tylosin. The clinical revelance of this reduced suscebtibility is not fully explored. Cross-resistance between tylvalosin & other macrolide antibiotics cannot be excluded.
It is used for:
• Treatment of swine enzootic pneumonia caused by susceptible strains of Mycoplasma hyopneumoniae.
• Treatment of porcine proliferative enteropathy (Ileitis) caused by Lawsonia intracellularis.
• Treatment of clinical outbreaks of swine dysentry caused by Brachyspira hyodysenteriae.
Pigs
Taken orally via feed
For whole product:
For treatment of Swine Enzootic Pneumonia : 125 gm of product / Ton feed for 7 consecutive days.
For treatment of Porcine Proliferative Enteropathy (ileitis) :250 gm of product/ Ton feed for 10 consecutive days
For treatment of swine Dysentery: 250 gm of product/ Ton feed/ day for 10 consecutive days
Meat and offal : 2 days
Store at temperature not exceeding 30°C, in dry place and used immediately after opening
Plastic Jar 100, 250, 500, 1000gm. 5 and 10 kg