Mectinoprinos
Zuxasulmarty
Composition :
Each mL contains:
Eprinomectin 5 mg
Properties:
Eprinomectin is a molecule with an endectocidal activity belonging to the macrocyclic lactone class. Compounds of the class bind with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve or muscle cells. These compounds bind selectively to these channels, which leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite .Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter GABA (gamma-aminobutyric acid).
Indications:
Treatment of infestations by the following parasites sensitive to eprinomectin:
•Gastrointestinal roundworms
–Ostertagia ostertagi (Adult-L4-Inhibited L4)
–Ostertagia lyata ( Adult )
–Haemonchus placei ( Adult-L4 )
–Trichostrongylus axei ( Adult-L4)
–Trichostrongylus colubriformis ( Adult-L4 )
–Cooperia spp. (Adult-L4-Inhibited L4)
–Cooperia oncophora ( Adult-L4 )
–Cooperia punctate ( Adult-L4 )
–Cooperia penctinata ( Adult-L4 )
– Cooperia surnabada ( Adult-L4 )
–Bunostomum phlebotomum ( Adult-L4 )
–Nematodirus helvetianus ( Adult-L4 )
–Oesophagostomum radiatum ( Adult-L4 )
–Oesophagagostomum spp. ( Adult )
–Trichuris discolor ( Adult )
•Lung worms
–Dictyocalus viviparous ( Adult-L4 )
• Warbles (parasitic stages):
-Hypoderma lineatum
-Hypoderma bovis
• Mange mites:
-Chorioptes bovis
-Sarcoptes scabiei var.bovis.
• Suking lice:
-Linognathus vituli
-Haematopinus eurysternus
-Solenopotes capillatus.
• Biting lice :
-Bovicola (Damalinia) bovis.
• Horn flies :
-Haemetobia irritans .
The product protects the animals against reinfestations with:
– Nematodirus helvetianus for 14 days.
– Trichostrongylus axei for 21 days.
– Dictyocaulus viviparus, Haemonchus placei, Cooperia oncophora, Cooperia punctata, Cooperia surnabada, Oesophagostomum radiatum and Ostertagia ostertagi for 28 days.
The duration of persistent efficacy can be variable for Cooperia spp and H. placei 14 days after treatment in particular in young and lean animals at the time of treatment.
Target Species:
Cattle.
Dosage & route of administration:
Route of administration: Pour-on use.
For whole product:
– Topically in one single treatment at the dose rate of 1 ml per 10 kg bodyweight
Apply the pour-on solution along the backline in a narrow strip extending from the withers to the tail head.
Withdrawal Periods:
• Meat and offal: 15 days.
• Milk: zero hours.
Contra-indications:
• Avermectins may not be well tolerated in non-target species (including dogs, cats and horses). Cases of mortality are reported in dogs, especially Collies, bobtail and related breeds and crosses, and also in turtles/tortoises.
• Do not use in other animal species.
• Do not administer orally or by injection.
• Do not use in cases of hypersensitivity to the active substance or to any of the excipients
Interaction with other medicinal products and other forms of interaction:
•Since eprinomectin binds strongly to plasma proteins, this should be taken into account if it is used in association with other molecules having the same characteristics.
Storage:
•Store at temperature not exceeding 30°C .
Packaging:
White (HDPE) plastic bottle contains 50-100-150-250-500 & 1000 ml of product and closed by (HDPE) white plastic cap with induction seal (contain 3 layer from inside to outside : plastic film-aluminum film-carton)with an outer label
