Butizole
Amikamart
Maroliz
Composition :
Each ml contains
Butylscopolamine bromide 4 mg
Metamizole 500 mg
Properties:
Butylscopolamine bromide is a spasmolytic agent with particular activity on the smooth muscle of the digestive and urinary systems. It antagonises the actions of acetylcholine at the muscarinic receptor and also has some activity at nicotinic receptors. Its pharmacological profile is similar to atropine, the main member of this class.
Metamizole is a non-steroidal anti-inflammatory drug of the pyrazolone group and also has analgesic and anti-pyretic effects.
Indications:
- As an aid in the control of pain associated with simple equine colic and as a diagnostic aid in more severe equine colics.
- For the control of diarrhoea in horses and dogs particularly when pain or abdominal discomfort is present.
- For the control of pain associated with urinary obstruction in horses and dogs.
Target Species:
Horses and dogs
Dose for active ingredient:
Horses : 25 mg Metamizole per kg body weight, 0.2 mg Butylscopolamine bromide per kg body weight
Dogs : 50 mg Metamizole per kg body weight, 0.4 mg Butylscopolamine bromide per kg body weight
Dose for whole product:
Horses: 5 ml per 100 kg body weight by intravenous or intramuscular injection
Dogs: 0.1 ml per kg body weight by intravenous or intramuscular injection
Warnings:
Studies in laboratory animals (rabbit, rat) have not produced any evidence of a teratogenic effect.
No information on use during pregnancy in the target species is available and therefore this product should not be used.
Contra-indications
- Due to a risk of local reactions do not use the intramuscular route in horses.
- Do not use in case of hypersensitivity to the active substance or to any of the excipients.
- Do not use in horses suffering from paralytic ileus.
Side-Effects:
Lead to a decrease in mononucleosis (AGRANULOCYTOSIS )
In horses, a slight transient increase in heart rate may be observed due to the parasympatholytic activity of butylscopolaminiumbromide (hyoscine butylbromide).
Withdrawal Periods:
None
Storage:
Store in dry dark and place at temperature not exceeding to 30 o.
Packaging:
Vial of 50,100 and 250 ml
