Composition :

Each 1 g contains:
Chlortetracycline (as hydrochloride) 50 mg
Sulfamethoxypyridazine (as sodium salt) 50 mg

Properties:

Chlortetracycline is a broad-spectrum antibiotic from the tetracycline group. It works by inhibiting the protein synthesis of bacteria by binding reversibly to the 30S ribosomal fraction receptors. This leads to an inhibition of the binding of amino-acyl-tRNA to the ribosome S and thus to blocking the growth of the bacterial culture. Chlortetracycline has a predominantly bacteriostatic activity. This is exerted by a penetration of the substance into the bacterial cell by both passive and active diffusion. Chlortetracycline is primarily active against gram-positive and negative microorganisms, aerobic and anaerobic, as well as against Mycoplasma, Chlamidiae and Rickettsiae. Sulfamethoxypyridazine is a long acting sulphonamide with a very broad activity spectrum that also has anticoccidial properties. It is active against gram-positive and negative microorganisms and certain protozoa such as coccidia. Sulfamethoxypyridazine acts by blocking the biosynthesis of folic acid by inhibiting.
The incorporation of para-aminobenzoic acid into folic acid. Sulfamethoxypyridazine has a predominantly bacteriostatic activity.The spectrum of theoretical activity extends to both Gram-positive (Staphylococcus spp, Listeria spp …) and Gram-negative (Escherichia coli, Salmonella, Proteus, Enterobacter, Bordetella …) germs

Indications:

Pre-ruminant Calves: Treatment of bacterial enteritis (scours) caused by E. coli and Salmonella species and bacterial pneumonia (shipping fever complex) associated with Pasteurella species A. pleuropneumoniae (Haemophilus species), and Klebsiella species
Pigs: treatment of respiratory diseases associated with Mycoplasma hyopneumoniae, Steptococcus suis and toxigenic strains of Pasteurella multocida.
It is also used in the treatment of rhinitis due to Bordetella bronchiseptica and streptococcal meningitis
due to Streptococcus suis type II.

Target Species:

Pre-ruminant calves, pigs

Dosage & route of administration:

Route of administration: Orally via drinking water.
For whole product:
2 g of product/ 10 kg. b.wt. morning and evening every 12 hours for 3-5 days.

Warnings :

– The product is used only as water soluble powder and not used as feed additive powder.
– Tetracyclines or sulfonamides may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact.
– Allergic reactions to these substances can be serious.
– In case of known hypersensitivity to Tetracyclines or sulfonamides, do not handle this product.
– Handle this product with the recommended precautions to avoid the risk of exposure.
Wearing a mask, goggles and protective gloves is recommended when preparing the food. Avoid breathing dust and avoid contact with skin and eyes.
– In case of emergence, after exposure to the product, symptoms such as a rash, consult a doctor and show him the leaflet. Swelling of the face, lips or eyelids, or breathing difficulties are more serious symptoms and require urgent medical attention.

Withdrawal Periods:

Pigs: Meat and offal: 12 days.
-Pre-ruminant calves: Meat and offal: 12 days.
-It is not intended for milk producing dairy females.

Contra-indications:

– Do not use in case of known allergy to sulphonamides or any substance of the group of tetracyclines.
– Do not use in case of known resistance to Tetracyclines and / or sulfonamides.
– Do not use in animals with severe renal or hepatic impairment.

Side Effect:

-As with all Tetracyclines, allergic and photosensitivity reactions can rarely be observed.
Tetracyclines are potentially hepatotoxic and nephrotoxic in high doses

Storage:

Store at a temperature not exceeding 30°C in a dry place and used immediately after opening and Reconstitution

Packaging:

Transparent Plastic (LDPE) bag containing 100, 250, 500 and 1000 gm of the product in (HDPE) white Plastic jar closed with Aluminum seal in Jar neck with (HDPE) With white plastic Cap with an outer label without insert.