Martigent 50

Oral Solution

For Vet.Use Only

Composition :

Each ml contains:
Gentamicin Sulfate 60.3 mg equivalent to 50 mg of Gentamicin

Properties:

Gentamicin is an antibiotic belonging to the group of Aminoglycosides. It has bactericidal activity against Gram-positive and Gram-negative bacteria Such as Pseudomonas spp., Klebsiella spp., Pasteurella spp., Streptococcus spp., E. coli, Proteus spp., Salmonella spp., Staphylococci. Gentamicin may be active against bacteria, which are resistant to other aminoglycoside antibiotics ,Aminoglycosides are taken up into bacteria by an oxygen-dependent process and are therefore inactive against anaerobic bacteria. They are more active in alkaline media, which is of particular importance when treating urinary infections. Aminoglycosides show synergism with beta-lactam antibacterials .
Gentamicin, like the other aminoglycoside antibiotics, act on susceptible bacteria presumably by irreversibly binding to the 30S ribosomal subunit thereby inhibiting protein synthesis. It is considered to be an bactericidal antibiotic.

Indications:

In swine : For treatment of swine dysentery associated with Treponema hyodysenteriae.
In swine : For treatment of swine colibacillosis Caused by Escherichia coli

Target Species:

Swine

Dose for whole product:

a) For colibacillosis in neonates: 0.1 m1 from the product PO
b) Swine (weanling): 0.022 ml / kg in drinking water for 3 consecutive days
c) Swine dysentery : 0.044 ml / kg in drinking water for 3 consecutive days

Warnings and Precautions:

For use in swine drinking water only.
Do not store or offer medicated drinking water in rusty containers since the drug is quickly destroyed in such containers.
Medicated drinking water should be prepared daily and be the sole source of drinking water for 3 days.
Treatment may be repeated if dysentery recurs.
Do not slaughter treated swine for food for at least 3 days following treatment

Contra-indications

Aminoglycosides are contraindicated in animals who are hypersensitive to them, should be used with extreme caution in animals with preexisting renal disease with concomitant monitoring and dosage interval adjustments made and should be used with caution in animals with neuromuscular disorders

Side-effects:

Neurotoxic – Ototoxic – Nephrotoxic

Withdrawal periods:

Swine: 3 days before slaughter

Storage:

Store at a temperature not exceeding 30°C and used immediately after opening

Packaging:

Opaque white (HDPE) plastic bottle containing 20,25,50,100,150,200,250,300,500,1000 ml oral solution lined with red (HDPE) plastic film closed by white plastic (HDPE)cap with white ( LDPE ) foam linear with outer Label only without insert