Martsulfa
Martiroflox 2%
Neoxymart
Composition :
Each 1 gm contains:
Sulfamethazine Sodium 630 mg ( Equivalent to Sulfamethazine base 583.89 mg )
Sulfathiazole Sodium 315 mg ( Equivalent to Sulfathiazole base 290 mg )
Properties:
Sulfonamides are a group of complex synthetic organic chemical compounds with chemotherapeutic activity they have a common chemical nucleus which is essential for antibacterial. Sulfonamides have antibacterial activity against Gram positive like Staphylococcus aureus,Streptococcus agalactiae , Streptococcus dygalactine and Corynebacterium pygenes and Gram negative Escherichia coli ,Salmonella spp.,Klebsiella spp . and Pasteurella spp .Sulfonamides compete with para – amino benzoic acid (PABA) for enzyme that synthesizes dihydrofolic acid in bacteria. It is synergistic with trimethoprim. Bacteriostatic. like other sulfonamides, it has abroad spectrum of activity, including gram – positive bacteria, gram –negative bacteria, and some protozoa. However, When used alone, resistance is common
Indications:
Swine : Treatment of enteritis and respiratory diseases caused by bacteria sensitive to sulfamethazine and sulfathiazole such as Mycoplasma gallisepticum and E.coli
Cattle : Treatment of bacterial infections such as pneumonia, metritis, enteritis, foot rot, mastitis and shipping fever complex caused by P. Multocida and E. coli
Target Species:
CATTLE , SWINE
Dose for active ingredient:
Sulfamethazine : Cattle and Swine : 100 mg of Sulfamethazine base /Kg
Sulfathiazole : Cattle and Swine : 50 mg of Sulfathiazole base /Kg
Dose for whole product:
Swine : 1.7 gm of product / 10 kg BW in drinking water
Cattle : 1.7 gm of product / 10 kg BW in drinking water
Warnings and Precautions:
If improvement is not seen within 48 hours, medication should be discontinued and diagnosis and the treatment re-evaluated. Generally, treatment should not exceed 4 days.
Treated animals should have easy access to drinking water to maintain an adequate hydration and miction.
Do not administer in swine feed.
Contra-indications
- Do not administer to animals with known sensitivity to sulfonamides or with renal impairments.
- Severely dehydrated animals should not be treated with this drug.
- Do not use in lactating dairy cattle.
Side-effects:
Associated with sulfonamides include allergic reactions, Type II and Type III hypersensitivity, arthropathy , anemia , thrombocytopenia , hepatopathy , hypothyroidism ( with prolonged therapy ) , keratoconjunctivitis sicca , and skin reactions
Withdrawal periods:
Cattle: 10 days before slaughter
Swine: 10 days before slaughter.
Storage:
Store in dry place at room temperature and protected from direct sunlight.
Packaging:
Jar of 50,78, 100,150,200,250,500,1000 gm ,5 kg , 10kg , 15 kg and 25 kg
