Composition:

Each 100 gm contains:
Neomycin Sulphate 20 gm

Properties:

Neomycin is an antibiotic from the aminoglycoside family. Aminoglycosides have a broad antibacterial spectrum with good activity against Gram negative bacteria (E.coli, Salmonella spp,Klebsiella spp,Pseudomonas aerugenosa, Bordetella bronchiseptica, pasteurella spp, Bacteroides spp,Treponema hyodysenteriae,Mycoplasma spp) and less activity against Gram positive bacteria (Staphylococcus aureus , Streptococcus agalactiae , Streptococcus dysgalactiae , Corynebacterium pyogenes ,Clostridium Spp). This class of antimicrobials has no effect against anaerobic bacteria. Neomycin binds to the 30S subunit of the bacterial ribosome which disturbs the reading of the constituent code of the RNA messenger, and finally the synthesis bacterial protein. At high concentrations, it has been shown that aminoglycosides damage the cell wall, conferring bactericidal and bacteriostatic properties.

Indications:

for treatment it is used of:
Pre-ruminating calves: Scours caused by E. coli.
Pigs (weaned and fattening pigs): -Enteric Colibacillosis caused by E. coli.
Broiler chickens and Turkeys for meat production: -Intestinal Colibacillosis caused by E. coli.

Target Species:

Pre-ruminating calves, pigs (weaned and fattening pigs), Broiler chickens and Turkeys for meat production

Dosage & route of administration:

• Route of administration: Orally in drinking water in pigs (weaned and fattening pigs), Broiler chickens and Turkeys for meat production and milk replacer for Pre-ruminating calves.
Dose of Whole product:
• Pre-ruminating calves, pigs (weaned and fattening pigs): 1.8 to 2.7 g of powder per 25 kg of bodyweight every 12 hours for 3 to 5 consecutive days.
• Broiler chickens, Turkeys for meat production: 1.43 to 2.14 g of powder per 1 liters of drinking water per day for 3 to 5 consecutive days.

Contra-indication:

• Do not use in known cases of hypersensitivity to the active substance, to aminoglycosides or to any of the excipients.
• Do not use in cases of intestinal obstruction.

Drug-drug interactions:
• General anaesthetics and muscle relaxing products increase the neuro-blocking effect of aminoglycosides. This may cause paralysis and apnoea.
• Special care should be taken when using concurrently with diuretics and potentially oto- or nephrotoxic substances.

Side Effects:

None known.

Withdrawal Period:

• Pre-ruminating calves, pigs (weaned and fattening pigs): Meat and offal: 14 days.
• Broiler chickens, Turkeys for meat production: Meat and offal: 14 days

Storage conditions:

Store at a temperature not exceeding 30°C in dry place and used immediately after opening and Reconstitution

Packagings:

Transparent plastic (LDPE) Sachet containing 100 , 250 , 500 and 1000 gm Powder for Oral Solution in (HDPE) plastic Jars with an outer label with (HDPE) cap with aluminum seal with an outer label