Oxyflumar
Spiramar
(injectable solution)
Composition :
Each 1 ml contains:
Streptomycin Sulfate …. ………… 150 mg
-Dihydrostreptomycin Sulfate ……..150 mg
Properties:
Streptomycin and dihydrostreptomycin are antibacterial of Aminoglycoside group.
Streptomycin is a member of the amino glycoside group of antibiotics and is thought to act by entering the bacterial cell and combining irreversibly with ribosomal RNA. This combination interferes with protein synthesis including misreading of the amino-acid sequence and premature termination of the protein chain, resulting in the death of the bacteria.This product Is active against a wide range of Gram-negative organisms and some Gram–positive pathogens . It is indicated in the treatment of organisms sensitive to streptomycin . Among the more sensitive to streptomycin in Vitro are Actinobacillus equuli, A. lignieresii, Actinomyces bovis, Brucella spp, E. coli, Haemophilus spp, Klebsiella spp, Leptospira canicola and L. ictero-haemorrhagiae, Pseudomonas aeruginosa and some species of Proteus, Pasteurella and Salmonella.
Indications:
For treatment of:
Cattle:
Wooden tongue caused by Actinobacillus lignieresii.*
Leptospirosis caused by Leptospira Pomona.*
Sheep:
Campylobacter abortion caused by C.fetus and C.jejuni.*
Leptospira abortion caused by L. hardjo and L.pomona
Target Species:
Cattle & Sheep.
Route of Administration:
Route : by intramuscular injection only.
Dose for active:
Cattle&sheep
10 mg of active ingredients/kg.b.wt.
Dose for whole product:
Cattle&sheep
1 ml of product/30 kg.b.wt. for a maximum 3 days.
Warnings and precautions:
- Use of the product should be based on susceptibility testing of bacteria isolated from the animal. If this is not possible, therapy should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria.
- Take particular care when treating animals suffering from renal damage.
- Concurrent use with other potentially nephrotoxic drugs, such as diuretics, should be avoided.
Contra-indications
- Contraindicated in cases of known hypersensitivity to the active ingredients.
- Do not inject more than 10 ml of this product into any one injection site. Failure to heed this warning may lead to residues above the legal limit in food for human consumption.
- Do not use in sheep producing milk intended for human consumption
- Not to be used in newly born pet animals.
Adverse effects:
Excessive and prolonged administration can lead to interference with balance and hearing. In extreme cases the damage can be permanent. Cats are the most susceptible animals.
Withdrawal periods:
Cattle (Meat & Offal): 14 days
Cattle (Milk):48 hours
Sheep (Meat & Offal): 14 days
Sheep (Milk): Do not use in sheep producing milk intended for human consumption.
Storage condition:
- Do not store above 250C
- Protect from light
Packaging:
glass vial: 50, 100,250ml.
