Sulfacleer
Polvotracin
Sulfapoult
Composition :
Each 1ml contains:
Sulfadimethoxine Sodium 200 mg (Eq,to Sulfadimethoxine base 186.7mg).
Trimethoprim 40 mg.
Properties:
Sulfadimethoxine is long acting and broad spectrum sulfonamide , which also exhibits anticoccidial properties. It is active against Gram-positive bacteria as Staphylocococcus aureus, Streptocococcus agalactiae and Gram-negative bacteria as Escherichia coli, Salmonella and protozoa such as coccidia.
Trimethoprim belongs to the family of diaminopyrimidines. It is active against Streptococci and most Gram-negative bacteria asEscherichia coli, Salmonella spp and Klebsiella spp,.,)
The combination of these two active ingredients allows a sequential blocking of biosynthesis of folic acid. These two substances act sequentially on the route of synthesis of tetrahydrofolic acid. Sulfadimethoxine inhibiting incorporation of para-aminobenzoic acid in the folic acid, trimethoprim by specifically inhibiting microbial dehydrofolate reductase enzyme. The combination extend their spectrum of activity against both Gram- positive bacteria as Staphylococcus and Gram-negative bacteria (Escherichia coli, Salmonella spp, Proteus, Enterobacter spp ,and Bordtella
Indications:
It is used for treatment of:
Fowl cholera caused by : Pasteurella multocida.
Target Species:
Poultry (broiler chicken)
Route of Administration:
Taken orally via drinking water.
Dose for active ingredients:
18.68 to 37.36 mg of sulfadimethoxine and 4-8 mg of trimethoprim per kg of body weight per day for 5 consecutive days.
Dose for whole product:
1 to 2 ml per 10 kg bodyweight per day for 5 consecutive days.
Warnings and precautions:
- Drink heavily treated birds.
Contra-indications
- Do not use in case of hypersensitivity of sulfonamides and/ or trimethoprim.
- Do not use in laying birds producing eggs for human consumption (4 weeks before the start of lay and during it).
Adverse effects:
Adverse reactions to sulfonamides may be due to hypersensitivity or direct toxic effects. Possible hypersensitivity reactions include urticaria, angioedema, anaphylaxis, skin rashes, drug fever, polyarthritis, hemolytic anemia, and agranulocytosis .
Withdrawal periods:
Poultry (broiler chicken):
Meat: ( 10 days)
Eggs: in the absence of a waiting time for the eggs do not use in laying birds producing eggs for human consumption (4 weeks before the start of lay and during it).
Storage condition:
Keep in temperature not exceeding 30°C, away from moisture.
Packaging:
Plastic bottles : 100, 250, 500 ml & 1 Liter .
