Sologuardio 100 mg/ml
Solution for use in drinking water
For veterinary use only
Composition :
Each ml contain:
Doramectin 750 micrograms
Properties:
Doramectin is a fermentation-derived antiparasitic agent, which belongs to the avermectin class, and is closely related structurally to ivermectin. Both compounds share a wide spectrum of antiparasitic activity and produce a similar paralysis in nematodes and parasitic arthropods. Whilst it is not possible to assign a single mode of action to the avermectins, it is likely that the entire series share a common mechanism. In parasitic organisms the effect is mediated through a specific avermectin-binding site. The physiological response to avermectin binding is an increase in membrane permeability to chloride ions. In invertebrate nervous tissue an influx of chloride ions into the excitatory motor neurone in nematodes or muscle cell of arthropods results in hyperpolarisation and the elimination of signal transmission with resulting paralysis
Indications:
It is used for treatment of adult and immature (L4) stages of sensitive strains of the following internal parasites:
Barber’s pole worm Haemonchus contortus Stomach hair worm Trichostrongylus axei Small brown stomach worm Ostertagia circumcincta, 0. trifurcata, Black scour worm Trichostrongylus colubriformis, T. vitrinus Small intestinal worm Cooperia curficei, C.oncophoraThin-necked intestinal worm Nematodirus spathiger, N. filicollis; Intestinal thread worm Strongyloides papillosus; Large bowel worm Oesophagostomum venulosum;Whipworm Trichuris ovis Large lungworm Dictyocaulus Maria’ adults only
Target Species:
Sheep
Dosage & route of administration:
Route of administration : Orally ,Shake container before use.
For Whole product:
• 1 mL of product /5 kg.b.wt
Withdrawal Periods:
• MEAT- DO NOT USE less than 14 days before slaughter for human consumption.
• DO NOT USE in female sheep which are producing or may in the future produce milk or milk products for human consumption.
Contra-indications:
• DO NOT USE in female sheep which are producing or may in the future produce milk or milk products for human consumption.
• DO NOT USE in case of hypersensitivity to the active substance or any of the excipients.
• The product has been formulated specifically for oral administration for cattle. It should not be administered to other species as severe adverse reactions, including fatalities in dogs, may occur.
Drug-drug interaction:
• Not known.
Storage:
•Store at temperature not exceeding 30°C .Protect from direct sunlight
Packaging:
White (HDPE) plastic bottle contains 50-100-150-250-500 & 1000 ml of product and closed by (HDPE) white plastic cap with induction seal (contain 3 layer from inside to outside : plastic film-aluminum film-carton)with an outer label
